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Structure-activity relationships of cryptopleurine analogs with E-ring modifications as anti-hepatitis C virus agents
The tylophorine analog rac-cryptopleurine exhibited potent anti-hepatitis C virus (HCV) activity through allosteric regulation of ATPase activity of heat shock cognate protein 70 (Hsc70). We evaluated the impact of modifications on the E-ring of rac-cryptopleurine to the inhibitory activity against...
Tallennettuna:
| Julkaisussa: | Bioorg Med Chem |
|---|---|
| Päätekijät: | , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
Elsevier Ltd.
2018
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7172637/ https://ncbi.nlm.nih.gov/pubmed/29317151 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2017.12.027 |
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