Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions

Understanding the signaling pathways that regulate proliferation and differentiation of muscle progenitors is essential for successful cell transplantation for treatment of Duchenne muscular dystrophy. Here, we report that a γ-secretase inhibitor, DAPT (N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phen...

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Gepubliceerd in:Commun Biol
Hoofdauteurs: Sakai-Takemura, Fusako, Nogami, Ken’ichiro, Elhussieny, Ahmed, Kawabata, Kota, Maruyama, Yusuke, Hashimoto, Naohiro, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171165/
https://ncbi.nlm.nih.gov/pubmed/32313117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0904-6
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