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Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions

Understanding the signaling pathways that regulate proliferation and differentiation of muscle progenitors is essential for successful cell transplantation for treatment of Duchenne muscular dystrophy. Here, we report that a γ-secretase inhibitor, DAPT (N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phen...

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Bibliografiska uppgifter
I publikationen:Commun Biol
Huvudupphovsmän: Sakai-Takemura, Fusako, Nogami, Ken’ichiro, Elhussieny, Ahmed, Kawabata, Kota, Maruyama, Yusuke, Hashimoto, Naohiro, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2020
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171165/
https://ncbi.nlm.nih.gov/pubmed/32313117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0904-6
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