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Prostaglandin EP2 receptor downstream of Notch signaling inhibits differentiation of human skeletal muscle progenitors in differentiation conditions

Understanding the signaling pathways that regulate proliferation and differentiation of muscle progenitors is essential for successful cell transplantation for treatment of Duchenne muscular dystrophy. Here, we report that a γ-secretase inhibitor, DAPT (N-[N-(3,5-difluorophenacetyl-L-alanyl)]-S-phen...

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Detalhes bibliográficos
Publicado no:Commun Biol
Main Authors: Sakai-Takemura, Fusako, Nogami, Ken’ichiro, Elhussieny, Ahmed, Kawabata, Kota, Maruyama, Yusuke, Hashimoto, Naohiro, Takeda, Shin’ichi, Miyagoe-Suzuki, Yuko
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7171165/
https://ncbi.nlm.nih.gov/pubmed/32313117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-020-0904-6
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