The ABC exporter IrtAB imports and reduces mycobacterial siderophores

Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores to scavenge iron from host proteins(1). M. tuberculosis produces two classes of siderophores, lipid-bound mycobactin and soluble carboxymycobactin(2, 3)...

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Foilsithe in:Nature
Main Authors: Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A.J., Hürlimann, Lea M., Peters, Eike, Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2020
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Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170716/
https://ncbi.nlm.nih.gov/pubmed/32296173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2136-9
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