The ABC exporter IrtAB imports and reduces mycobacterial siderophores

Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores to scavenge iron from host proteins(1). M. tuberculosis produces two classes of siderophores, lipid-bound mycobactin and soluble carboxymycobactin(2, 3)...

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Bibliografske podrobnosti
izdano v:Nature
Main Authors: Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A.J., Hürlimann, Lea M., Peters, Eike, Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A.
Format: Artigo
Jezik:Inglês
Izdano: 2020
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170716/
https://ncbi.nlm.nih.gov/pubmed/32296173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2136-9
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