The ABC exporter IrtAB imports and reduces mycobacterial siderophores

Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores to scavenge iron from host proteins(1). M. tuberculosis produces two classes of siderophores, lipid-bound mycobactin and soluble carboxymycobactin(2, 3)...

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Détails bibliographiques
Publié dans:Nature
Auteurs principaux: Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A.J., Hürlimann, Lea M., Peters, Eike, Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A.
Format: Artigo
Langue:Inglês
Publié: 2020
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170716/
https://ncbi.nlm.nih.gov/pubmed/32296173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2136-9
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