The ABC exporter IrtAB imports and reduces mycobacterial siderophores

Intracellular replication of the deadly pathogen Mycobacterium tuberculosis relies on the production of small organic molecules called siderophores to scavenge iron from host proteins(1). M. tuberculosis produces two classes of siderophores, lipid-bound mycobactin and soluble carboxymycobactin(2, 3)...

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Publicat a:Nature
Autors principals: Arnold, Fabian M., Weber, Miriam S., Gonda, Imre, Gallenito, Marc J., Adenau, Sophia, Egloff, Pascal, Zimmermann, Iwan, Hutter, Cedric A.J., Hürlimann, Lea M., Peters, Eike, Piel, Jörn, Meloni, Gabriele, Medalia, Ohad, Seeger, Markus A.
Format: Artigo
Idioma:Inglês
Publicat: 2020
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170716/
https://ncbi.nlm.nih.gov/pubmed/32296173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41586-020-2136-9
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