Post-translational Acetylation of MbtA Modulates Mycobacterial Siderophore Biosynthesis

Iron is an essential element for life, but its soluble form is scarce in the environment and is rarer in the human body. Mtb (Mycobacterium tuberculosis) produces two aryl-capped siderophores, mycobactin (MBT) and carboxymycobactin (cMBT), to chelate intracellular iron. The adenylating enzyme MbtA c...

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Vydáno v:J Biol Chem
Hlavní autoři: Vergnolle, Olivia, Xu, Hua, Tufariello, JoAnn M., Favrot, Lorenza, Malek, Adel A., Jacobs, William R., Blanchard, John S.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Microbiology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064009/
https://ncbi.nlm.nih.gov/pubmed/27566542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.744532
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