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Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2
Pyruvate kinase muscle isoform 2 (PKM2) is a key glycolytic enzyme involved in ATP generation and critical for cancer metabolism. PKM2 is expressed in many human cancers and is regulated by complex mechanisms that promote tumor growth and proliferation. Therefore, it is considered an attractive ther...
में बचाया:
| में प्रकाशित: | J Biol Chem |
|---|---|
| मुख्य लेखकों: | , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society for Biochemistry and Molecular Biology
2020
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7170521/ https://ncbi.nlm.nih.gov/pubmed/32144209 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA120.013030 |
| टैग : |
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