A carregar...
Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2
Dichloroacetate (DCA) is a promising anticancer and antidiabetic compound targeting the mitochondrial pyruvate dehydrogenase kinase (PDHK). This study was undertaken in order to map the DCA-binding site of PDHK2. Here, we present evidence that R114, S83, I157 and, to some extent, H115 are essential...
Na minha lista:
| Main Authors: | , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2007
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950259/ https://ncbi.nlm.nih.gov/pubmed/17544412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.05.052 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|