Načítá se...
Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2
Dichloroacetate (DCA) is a promising anticancer and antidiabetic compound targeting the mitochondrial pyruvate dehydrogenase kinase (PDHK). This study was undertaken in order to map the DCA-binding site of PDHK2. Here, we present evidence that R114, S83, I157 and, to some extent, H115 are essential...
Uloženo v:
| Hlavní autoři: | , , |
|---|---|
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2007
|
| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1950259/ https://ncbi.nlm.nih.gov/pubmed/17544412 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2007.05.052 |
| Tagy: |
Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!
|