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Allosteric Coupling in Pyruvate Dehydrogenase Kinase 2
Mitochondrial pyruvate dehydrogenase kinase 2 (PDHK2) phosphorylates the pyruvate dehydrogenase multienzyme complex (PDC) and thereby controls the rate of oxidative decarboxylation of pyruvate. The activity of PDHK2 is regulated by a variety of metabolites such as pyruvate, NAD(+), NADH, CoA, and ac...
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| Hauptverfasser: | , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2568900/ https://ncbi.nlm.nih.gov/pubmed/18627174 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi800631h |
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