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Heterotrimeric G(q) proteins as therapeutic targets?

Heterotrimeric G proteins are the core upstream elements that transduce and amplify the cellular signals from G protein–coupled receptors (GPCRs) to intracellular effectors. GPCRs are the largest family of membrane proteins encoded in the human genome and are the targets of about one-third of prescr...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Kostenis, Evi, Pfeil, Eva Marie, Annala, Suvi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7170519/
https://ncbi.nlm.nih.gov/pubmed/32122969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.007061
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