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The G(q) and G(12) Families of Heterotrimeric G Proteins Report Functional Selectivity
Receptors coupled to the G(q) and G(12) families of heterotrimeric G proteins have surfaced rarely in the context of functional selectivity and always indirectly. We explore here the differential engagement of G(q) and G(13) (of the G(12) family) by the thromboxane A(2) receptor α (TPα), via agonist...
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| 主要な著者: | , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685064/ https://ncbi.nlm.nih.gov/pubmed/18952767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.050906 |
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