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The G(q) and G(12) Families of Heterotrimeric G Proteins Report Functional Selectivity
Receptors coupled to the G(q) and G(12) families of heterotrimeric G proteins have surfaced rarely in the context of functional selectivity and always indirectly. We explore here the differential engagement of G(q) and G(13) (of the G(12) family) by the thromboxane A(2) receptor α (TPα), via agonist...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Pharmacology and Experimental Therapeutics
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2685064/ https://ncbi.nlm.nih.gov/pubmed/18952767 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.108.050906 |
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