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Identification of tetranectin-targeting monoclonal antibodies to treat potentially lethal sepsis.
For the clinical management of sepsis, antibody-based strategies have only been attempted to antagonize pro-inflammatory cytokines, but not yet been tried to target harmless proteins that may interact with these pathogenic mediators. Here we report an antibody strategy to intervene in the harmful in...
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| Udgivet i: | Sci Transl Med |
|---|---|
| Main Authors: | , , , , , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2020
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7169984/ https://ncbi.nlm.nih.gov/pubmed/32295901 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/scitranslmed.aaz3833 |
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