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Spermine Protects Mice Against Lethal Sepsis Partly by Attenuating Surrogate Inflammatory Markers

The pathogenesis of sepsis is partly attributable to dysregulated inflammatory response mediated by pathogen-associated molecular patterns (PAMPs) (for example, endotoxin) and damage-associated molecular patterns (DAMPs) (for example, high-mobility group box 1 [HMGB1]). An endogenous ubiquitous poly...

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Hlavní autoři: Zhu, Shu, Ashok, Mala, Li, Jianhua, Li, Wei, Yang, Huan, Wang, Ping, Tracey, Kevin J, Sama, Andrew E, Wang, Haichao
Médium: Artigo
Jazyk:Inglês
Vydáno: ScholarOne 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2707519/
https://ncbi.nlm.nih.gov/pubmed/19593412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2119/molmed.2009.00062
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