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Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review

It is over 50 years since the discovery of microtubules, and they have become one of the most important drug targets for anti-cancer therapies. Microtubules are predominantly composed of the protein tubulin, which contains a number of different binding sites for small-molecule drugs. There is contin...

詳細記述

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書誌詳細
出版年:Pharmaceuticals (Basel)
主要な著者: McLoughlin, Eavan C., O’Boyle, Niamh M.
フォーマット: Artigo
言語:Inglês
出版事項: MDPI 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168938/
https://ncbi.nlm.nih.gov/pubmed/31947889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13010008
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