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Colchicine-Binding Site Inhibitors from Chemistry to Clinic: A Review

It is over 50 years since the discovery of microtubules, and they have become one of the most important drug targets for anti-cancer therapies. Microtubules are predominantly composed of the protein tubulin, which contains a number of different binding sites for small-molecule drugs. There is contin...

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Detalhes bibliográficos
Publicado no:Pharmaceuticals (Basel)
Main Authors: McLoughlin, Eavan C., O’Boyle, Niamh M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7168938/
https://ncbi.nlm.nih.gov/pubmed/31947889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph13010008
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