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Insight into the activity of SARS main protease: Molecular dynamics study of dimeric and monomeric form of enzyme

The phenomenon that SARS coronavirus main protease (SARS M(pro)) dimer is the main functional form has been confirmed by experiment. However, because of the absence of structural information of the monomer, the reasons for this remain unknown. To investigate it, two molecular dynamics (MD) simulatio...

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Detalles Bibliográficos
Publicado en:Proteins
Autores principales: Zheng, Kewen, Ma, Guozheng, Zhou, Jinming, Zen, Min, Zhao, Wenna, Jiang, Yongjun, Yu, Qingsen, Feng, Jialiang
Formato: Artigo
Lenguaje:Inglês
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2006
Materias:
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7167853/
https://ncbi.nlm.nih.gov/pubmed/17083088
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.21160
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