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Prevention and rescue of cardiac dysfunction by methanocarba adenosine monophosphonate derivatives

Accumulating evidence supports a therapeutic role of purinergic signaling in cardiac diseases. Previously, efficacy of systemically infused MRS2339, a charged methanocarba derivative of 2-Cl-adenosine monophosphate, was demonstrated in animal models of heart failure. We now test the hypothesis that...

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Dades bibliogràfiques
Publicat a:Purinergic Signal
Autors principals: Shen, Jian-Bing, Toti, Kiran S., Chakraborty, Saibal, Kumar, T. Santhosh, Cronin, Chunxia, Liang, Bruce T., Jacobson, Kenneth A.
Format: Artigo
Idioma:Inglês
Publicat: Springer Netherlands 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7166228/
https://ncbi.nlm.nih.gov/pubmed/31989534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11302-020-09688-0
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