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Stepwise promoter melting by bacterial RNA polymerase
Transcription initiation requires formation of the open promoter complex, RPo. To generate RPo, RNA polymerase (RNAP) unwinds the DNA duplex to form the transcription bubble and loads the DNA into the RNAP active site. RPo formation is a multi-step process with transient intermediates of unknown str...
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| Pubblicato in: | Mol Cell |
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| Autori principali: | , , , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2020
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7166197/ https://ncbi.nlm.nih.gov/pubmed/32160514 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2020.02.017 |
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