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E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation
TraR and its homolog DksA are bacterial proteins that regulate transcription initiation by binding directly to RNA polymerase (RNAP) rather than to promoter DNA. Effects of TraR mimic the combined effects of DksA and its cofactor ppGpp, but the structural basis for regulation by these factors remain...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6970531/ https://ncbi.nlm.nih.gov/pubmed/31841111 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49375 |
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