E. coli TraR allosterically regulates transcription initiation by altering RNA polymerase conformation

TraR and its homolog DksA are bacterial proteins that regulate transcription initiation by binding directly to RNA polymerase (RNAP) rather than to promoter DNA. Effects of TraR mimic the combined effects of DksA and its cofactor ppGpp, but the structural basis for regulation by these factors remain...

Cur síos iomlán

Na minha lista:
Sonraí Bibleagrafaíochta
Foilsithe in:eLife
Main Authors: Chen, James, Gopalkrishnan, Saumya, Chiu, Courtney, Chen, Albert Y, Campbell, Elizabeth A, Gourse, Richard L, Ross, Wilma, Darst, Seth A
Formáid: Artigo
Teanga:Inglês
Foilsithe: eLife Sciences Publications, Ltd 2019
Ábhair:
Biochemistry and Chemical Biology
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970531/
https://ncbi.nlm.nih.gov/pubmed/31841111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.49375
Clibeanna: Cuir Clib Leis
Gan Chlibeanna, Bí ar an gcéad duine leis an taifead seo a chlibeáil!

Míreanna Comhchosúla