Native mass spectrometry-based screening for optimal sample preparation in single particle cryo-EM

Recent advances in single particle cryogenic electron microscopy (cryo-EM) have enabled the structural determination of numerous protein assemblies at high resolution, yielding unprecedented insights into their function. However, despite its extraordinary capabilities, cryo-EM remains time-consuming...

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Detalhes bibliográficos
Publicado no:Structure
Main Authors: Olinares, Paul Dominic B., Kang, Jin Young, Llewellyn, Eliza, Chiu, Courtney, Chen, James, Malone, Brandon, Saecker, Ruth M., Campbell, Elizabeth A., Darst, Seth A., Chait, Brian T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7867593/
https://ncbi.nlm.nih.gov/pubmed/33217329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2020.11.001
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