Structural basis for transcription complex disruption by the Mfd translocase

Transcription-coupled repair (TCR) is a sub-pathway of nucleotide excision repair (NER) that preferentially removes lesions from the template-strand (t-strand) that stall RNA polymerase (RNAP) elongation complexes (ECs). Mfd mediates TCR in bacteria by removing the stalled RNAP concealing the lesion...

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Publicat a:eLife
Autors principals: Kang, Jin Young, Llewellyn, Eliza, Chen, James, Olinares, Paul Dominic B, Brewer, Joshua, Chait, Brian T, Campbell, Elizabeth A, Darst, Seth A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2021
Matèries:
Structural Biology and Molecular Biophysics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7864632/
https://ncbi.nlm.nih.gov/pubmed/33480355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.62117
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