uPAR antibody (huATN-658) and Zometa reduce breast cancer growth and skeletal lesions

Urokinase plasminogen activator receptor (uPAR) is implicated in tumor growth and metastasis due to its ability to activate latent growth factors, proteases, and different oncogenic signaling pathways upon binding to different ligands. Elevated uPAR expression is correlated with the increased aggres...

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Podrobná bibliografie
Vydáno v:Bone Res
Hlavní autoři: Mahmood, Niaz, Arakelian, Ani, Khan, Haseeb Ahmed, Tanvir, Imrana, Mazar, Andrew P., Rabbani, Shafaat A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165173/
https://ncbi.nlm.nih.gov/pubmed/32337090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-020-0094-3
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