An Anti-Urokinase Plasminogen Activator Receptor Antibody (ATN-658) Blocks Prostate Cancer Invasion, Migration, Growth, and Experimental Skeletal Metastasis In Vitro and In Vivo

Urokinase plasminogen activator receptor (uPAR) is a multidomain protein that plays important roles in the growth, invasion, and metastasis of a number of cancers. In the present study, we examined the effects of administration of a monoclonal anti-uPAR antibody (ATN-658) on prostate cancer progress...

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Main Authors: Rabbani, Shafaat A, Ateeq, Bushra, Arakelian, Ani, Valentino, Maria Luisa, Shaw, David E, Dauffenbach, Lisa M, Kerfoot, Christopher A, Mazar, Andrew P
Format: Artigo
Sprog:Inglês
Udgivet: Neoplasia Press Inc. 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950327/
https://ncbi.nlm.nih.gov/pubmed/20927316
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