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Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

DNA hypomethylation coordinately targets various signaling pathways involved in tumor growth and metastasis. At present, there are no approved therapeutic modalities that target hypomethylation. In this regard, we examined the therapeutic plausibility of using universal methyl group donor S-adenosyl...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Mahmood, Niaz, Cheishvili, David, Arakelian, Ani, Tanvir, Imrana, Khan, Haseeb Ahmed, Pépin, Anne-Sophie, Szyf, Moshe, Rabbani, Shafaat A.
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797041/
https://ncbi.nlm.nih.gov/pubmed/29435170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23704
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