Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

DNA hypomethylation coordinately targets various signaling pathways involved in tumor growth and metastasis. At present, there are no approved therapeutic modalities that target hypomethylation. In this regard, we examined the therapeutic plausibility of using universal methyl group donor S-adenosyl...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Mahmood, Niaz, Cheishvili, David, Arakelian, Ani, Tanvir, Imrana, Khan, Haseeb Ahmed, Pépin, Anne-Sophie, Szyf, Moshe, Rabbani, Shafaat A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2017
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797041/
https://ncbi.nlm.nih.gov/pubmed/29435170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23704
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