S-adenosylmethionine blocks osteosarcoma cells proliferation and invasion in vitro and tumor metastasis in vivo: therapeutic and diagnostic clinical applications

Osteosarcoma (OS) is an aggressive and highly metastatic form of primary bone cancer affecting young children and adults. Previous studies have shown that hypomethylation of critical genes is driving metastasis. Here, we examine whether hypermethylation treatment can block OS growth and pulmonary me...

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Bibliografiska uppgifter
I publikationen:Cancer Med
Huvudupphovsmän: Parashar, Surabhi, Cheishvili, David, Arakelian, Ani, Hussain, Zahid, Tanvir, Imrana, Khan, Haseeb Ahmed, Szyf, Moshe, Rabbani, Shafaat A
Materialtyp: Artigo
Språk:Inglês
Publicerad: BlackWell Publishing Ltd 2015
Ämnen:
Cancer Biology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4430266/
https://ncbi.nlm.nih.gov/pubmed/25619880
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cam4.386
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