Methyl donor S-adenosylmethionine (SAM) supplementation attenuates breast cancer growth, invasion, and metastasis in vivo; therapeutic and chemopreventive applications

DNA hypomethylation coordinately targets various signaling pathways involved in tumor growth and metastasis. At present, there are no approved therapeutic modalities that target hypomethylation. In this regard, we examined the therapeutic plausibility of using universal methyl group donor S-adenosyl...

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Detalles Bibliográficos
Publicado en:Oncotarget
Main Authors: Mahmood, Niaz, Cheishvili, David, Arakelian, Ani, Tanvir, Imrana, Khan, Haseeb Ahmed, Pépin, Anne-Sophie, Szyf, Moshe, Rabbani, Shafaat A.
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2017
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5797041/
https://ncbi.nlm.nih.gov/pubmed/29435170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.23704
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