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RETRACTED ARTICLE: β adrenergic receptor modulated signaling in glioma models: promoting β adrenergic receptor-β arrestin scaffold-mediated activation of extracellular-regulated kinase 1/2 may prove to be a panacea in the treatment of intracranial and spinal malignancy and extra-neuraxial carcinoma

Neoplastically transformed astrocytes express functionally active cell surface β adrenergic receptors (βARs). Treatment of glioma models in vitro and in vivo with β adrenergic agonists variably amplifies or attenuates cellular proliferation. In the majority of in vivo models, β adrenergic agonists g...

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Enregistré dans:
Détails bibliographiques
Publié dans:Mol Biol Rep
Auteurs principaux: Ghali, George Zaki, Ghali, Michael George Zaki
Format: Artigo
Langue:Inglês
Publié: Springer Netherlands 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7165076/
https://ncbi.nlm.nih.gov/pubmed/32303958
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11033-020-05427-1
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