β-arrestin–biased signaling through the β(2)-adrenergic receptor promotes cardiomyocyte contraction

β-adrenergic receptors (βARs) are critical regulators of acute cardiovascular physiology. In response to elevated catecholamine stimulation during development of congestive heart failure (CHF), chronic activation of G(s)-dependent β(1)AR and G(i)-dependent β(2)AR pathways leads to enhanced cardiomyo...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Carr, Richard, Schilling, Justin, Song, Jianliang, Carter, Rhonda L., Du, Yang, Yoo, Sungsoo M., Traynham, Christopher J., Koch, Walter J., Cheung, Joseph Y., Tilley, Douglas G., Benovic, Jeffrey L.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2016
Assuntos:
PNAS Plus
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4948363/
https://ncbi.nlm.nih.gov/pubmed/27354517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1606267113
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