Frequent alterations in p16/CDKN2A identified by immunohistochemistry and FISH in chordoma

The expression of p16/CDKN2A, the second most commonly inactivated tumour suppressor gene in cancer, is lost in the majority of chordomas. However, the mechanism(s) leading to its inactivation and contribution to disease progression have only been partially addressed using small patient cohorts. We...

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Detalhes bibliográficos
Publicado no:J Pathol Clin Res
Main Authors: Cottone, Lucia, Eden, Nadia, Usher, Inga, Lombard, Patrick, Ye, Hongtao, Ligammari, Lorena, Lindsay, Daniel, Brandner, Sebastian, Pižem, Jože, Pillay, Nischalan, Tirabosco, Roberto, Amary, Fernanda, Flanagan, Adrienne M
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Inc. 2020
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7164370/
https://ncbi.nlm.nih.gov/pubmed/31916407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cjp2.156
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