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EGFR inhibitors identified as a potential treatment for chordoma in a focused compound screen

Chordoma is a rare malignant bone tumour with a poor prognosis and limited therapeutic options. We undertook a focused compound screen (FCS) against 1097 compounds on three well‐characterized chordoma cell lines; 154 compounds were selected from the single concentration screen (1 µm), based on their...

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書目詳細資料
發表在:J Pathol
Main Authors: Scheipl, Susanne, Barnard, Michelle, Cottone, Lucia, Jorgensen, Mette, Drewry, David H, Zuercher, William J, Turlais, Fabrice, Ye, Hongtao, Leite, Ana P, Smith, James A, Leithner, Andreas, Möller, Peter, Brüderlein, Silke, Guppy, Naomi, Amary, Fernanda, Tirabosco, Roberto, Strauss, Sandra J, Pillay, Nischalan, Flanagan, Adrienne M
格式: Artigo
語言:Inglês
出版: John Wiley & Sons, Ltd 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4922416/
https://ncbi.nlm.nih.gov/pubmed/27102572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4729
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