Isocitrate dehydrogenase 1 mutations (IDH1) and p16/CDKN2A copy number change in conventional chondrosarcomas

To determine whether IDH1 mutations are present in primary and relapsed (local and distal) conventional central chondrosarcomas; and secondly, to assess if loss of p16/CDKN2A is associated with tumour grade progression, 102 tumour samples from 37 patients, including material from presenting and rela...

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Bibliografski detalji
Izdano u:Virchows Arch
Glavni autori: Amary, M. Fernanda, Ye, Hongtao, Forbes, Georgina, Damato, Stephen, Maggiani, Francesca, Pollock, Robin, Tirabosco, Roberto, Flanagan, Adrienne M.
Format: Artigo
Jezik:Inglês
Izdano: Springer Berlin Heidelberg 2014
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4325180/
https://ncbi.nlm.nih.gov/pubmed/25432631
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00428-014-1685-4
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