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Understanding the drug exposure–response relationship of bedaquiline to predict efficacy for novel dosing regimens in the treatment of multidrug‐resistant tuberculosis
AIMS: To externally validate an earlier characterized relationship between bedaquiline exposure and decline in bacterial load in a more difficult‐to‐treat patient population, and to explore the performances of alternative dosing regimens through simulations. METHODS: The bedaquiline exposure–respons...
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| Publicado no: | Br J Clin Pharmacol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7163373/ https://ncbi.nlm.nih.gov/pubmed/31840278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.14199 |
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