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Modelling of mycobacterial load reveals bedaquiline’s exposure–response relationship in patients with drug-resistant TB
BACKGROUND: Bedaquiline has been shown to reduce time to sputum culture conversion (SCC) and increase cure rates in patients with drug-resistant TB, but the influence of drug exposure remains uncharacterized. OBJECTIVES: To investigate whether an exposure–response relationship could be characterized...
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| Publicado no: | J Antimicrob Chemother |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5890768/ https://ncbi.nlm.nih.gov/pubmed/28961790 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx317 |
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