Modelling of mycobacterial load reveals bedaquiline’s exposure–response relationship in patients with drug-resistant TB

BACKGROUND: Bedaquiline has been shown to reduce time to sputum culture conversion (SCC) and increase cure rates in patients with drug-resistant TB, but the influence of drug exposure remains uncharacterized. OBJECTIVES: To investigate whether an exposure–response relationship could be characterized...

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Detaylı Bibliyografya
Yayımlandı:J Antimicrob Chemother
Asıl Yazarlar: Svensson, Elin M, Karlsson, Mats O
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Oxford University Press 2017
Konular:
Original Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC5890768/
https://ncbi.nlm.nih.gov/pubmed/28961790
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dkx317
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