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Mass spectrometry-based methods in characterization of the higher order structure of protein therapeutics

Higher order structure of protein therapeutics is an important quality attribute, which dictates both potency and safety. While modern experimental biophysics offers an impressive arsenal of state-of-the-art tools that can be used for the characterization of higher order structure, many of them are...

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Detalhes bibliográficos
Publicado no:J Pharm Biomed Anal
Main Authors: Kaltashov, Igor A., Bobst, Cedric E., Pawlowski, Jake, Wang, Guanbo
Formato: Artigo
Idioma:Inglês
Publicado em: 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162711/
https://ncbi.nlm.nih.gov/pubmed/32092629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2020.113169
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