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Mass spectrometry-based methods in characterization of the higher order structure of protein therapeutics

Higher order structure of protein therapeutics is an important quality attribute, which dictates both potency and safety. While modern experimental biophysics offers an impressive arsenal of state-of-the-art tools that can be used for the characterization of higher order structure, many of them are...

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Bibliographische Detailangaben
Veröffentlicht in:J Pharm Biomed Anal
Hauptverfasser: Kaltashov, Igor A., Bobst, Cedric E., Pawlowski, Jake, Wang, Guanbo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162711/
https://ncbi.nlm.nih.gov/pubmed/32092629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jpba.2020.113169
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