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Advances and challenges in analytical characterization of biotechnology products: mass spectrometry-based approaches to study properties and behavior of protein therapeutics

Biopharmaceuticals are a unique class of medicines due to their extreme structural complexity. The structure of these therapeutic proteins is critically important for their efficacy and safety, and the ability to characterize it at various levels (from sequence to conformation) is critical not only...

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Detalhes bibliográficos
Main Authors: Kaltashov, Igor A., Bobst, Cedric E., Abzalimov, Rinat R., Wang, Guanbo, Baykal, Burcu, Wang, Shunhai
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176981/
https://ncbi.nlm.nih.gov/pubmed/21619926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biotechadv.2011.05.006
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