Novel M(2)‐selective, G(i)‐biased agonists of muscarinic acetylcholine receptors

BACKGROUND AND PURPOSE: More than 30% of currently marketed medications act via GPCRs. Thus, GPCRs represent one of the most important pharmacotherapeutic targets. In contrast to traditional agonists activating multiple signalling pathways, agonists activating a single signalling pathway represent a...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Br J Pharmacol
Päätekijät: Randáková, Alena, Nelic, Dominik, Ungerová, Dana, Nwokoye, Peter, Su, Qiwen, Doležal, Vladimír, El‐Fakahany, Esam E., Boulos, John, Jakubík, Jan
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: John Wiley and Sons Inc. 2020
Aiheet:
Research Papers
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161557/
https://ncbi.nlm.nih.gov/pubmed/31910288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14970
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