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Establishment of 5′–3′ interactions in mRNA independent of a continuous ribose-phosphate backbone

Functions of eukaryotic mRNAs are characterized by intramolecular interactions between their ends. We have addressed the question whether 5′ and 3′ ends meet by diffusion-controlled encounter “through solution” or by a mechanism involving the RNA backbone. For this purpose, we used a translation sys...

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Publicat a:RNA
Autors principals: Kluge, Florian, Götze, Michael, Wahle, Elmar
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2020
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7161349/
https://ncbi.nlm.nih.gov/pubmed/32111664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.073759.119
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