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Oligoadenylation of 3′ decay intermediates promotes cytoplasmic mRNA degradation in Drosophila cells

Post-transcriptional 3′ end addition of nucleotides is important in a variety of RNA decay pathways. We have examined the 3′ end addition of nucleotides during the decay of the Hsp70 mRNA and a corresponding reporter RNA in Drosophila S2 cells by conventional sequencing of cDNAs obtained after mRNA...

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Detalhes bibliográficos
Publicado no:RNA
Main Authors: Harnisch, Christiane, Cuzic-Feltens, Simona, Dohm, Juliane C., Götze, Michael, Himmelbauer, Heinz, Wahle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4748820/
https://ncbi.nlm.nih.gov/pubmed/26786835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.053942.115
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