Maturation of mammalian H/ACA box snoRNAs: PAPD5-dependent adenylation and PARN-dependent trimming

Small nucleolar and small Cajal body RNAs (snoRNAs and scaRNAs) of the H/ACA box and C/D box type are generated by exonucleolytic shortening of longer precursors. Removal of the last few nucleotides at the 3′ end is known to be a distinct step. We report that, in human cells, knock-down of the poly(...

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Main Authors: Berndt, Heike, Harnisch, Christiane, Rammelt, Christiane, Stöhr, Nadine, Zirkel, Anne, Dohm, Juliane C., Himmelbauer, Heinz, Tavanez, Joao-Paulo, Hüttelmaier, Stefan, Wahle, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: Cold Spring Harbor Laboratory Press 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3334704/
https://ncbi.nlm.nih.gov/pubmed/22442037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.032292.112
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