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β-Phenethyl Isothiocyanate Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the MAPK Signaling Pathway

Osteosarcoma is the most common primary malignancy of the skeleton in children and adults. The outcomes of people with osteosarcomas are unsatisfied. β-Phenethyl isothiocyanate (PEITC) exhibits chemoprevention and chemotherapeutic activities against many human cancers. The molecular mechanism underl...

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Detalhes bibliográficos
Publicado no:Oxid Med Cell Longev
Main Authors: Lv, Huanhuan, Zhen, Chenxiao, Liu, Junyu, Shang, Peng
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160723/
https://ncbi.nlm.nih.gov/pubmed/32322335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5021983
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