A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous tumor having various genetic alterations. The current treatment options had limited impact on disease free survival due to therapeutic resistance. Novel anticancer agents are needed to treat CRC specifically metastatic colorectal cancer. A novel...

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Enregistré dans:
Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Al-Khayal, Khayal, Vaali-Mohammed, Mansoor-Ali, Elwatidy, Mohammed, Bin Traiki, Thamer, Al-Obeed, Omar, Azam, Mohammad, Khan, Zahid, Abdulla, Maha, Ahmad, Rehan
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2020
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376665/
https://ncbi.nlm.nih.gov/pubmed/32703189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07165-w
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