A novel coordination complex of platinum (PT) induces cell death in colorectal cancer by altering redox balance and modulating MAPK pathway

BACKGROUND: Colorectal cancer (CRC) is a heterogeneous tumor having various genetic alterations. The current treatment options had limited impact on disease free survival due to therapeutic resistance. Novel anticancer agents are needed to treat CRC specifically metastatic colorectal cancer. A novel...

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Publicado en:BMC Cancer
Main Authors: Al-Khayal, Khayal, Vaali-Mohammed, Mansoor-Ali, Elwatidy, Mohammed, Bin Traiki, Thamer, Al-Obeed, Omar, Azam, Mohammad, Khan, Zahid, Abdulla, Maha, Ahmad, Rehan
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2020
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7376665/
https://ncbi.nlm.nih.gov/pubmed/32703189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-020-07165-w
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