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Novel derivative of aminobenzenesulfonamide (3c) induces apoptosis in colorectal cancer cells through ROS generation and inhibits cell migration

BACKGROUND: Colorectal cancer (CRC) is the 3(rd) most common type of cancer worldwide. New anti-cancer agents are needed for treating late stage colorectal cancer as most of the deaths occur due to cancer metastasis. A recently developed compound, 3c has shown to have potent antitumor effect; howeve...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Al-Khayal, Khayal, Alafeefy, Ahmed, Vaali-Mohammed, Mansoor-Ali, Mahmood, Amer, Zubaidi, Ahmed, Al-Obeed, Omar, Khan, Zahid, Abdulla, Maha, Ahmad, Rehan
Format: Artigo
Language:Inglês
Published: BioMed Central 2017
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5210304/
https://ncbi.nlm.nih.gov/pubmed/28049506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-016-3005-7
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