Novel quinazoline-based sulfonamide derivative (3D) induces apoptosis in colorectal cancer by inhibiting JAK2–STAT3 pathway

INTRODUCTION: Colorectal cancer (CRC) is a major worldwide health problem owing to its high prevalence and mortality rate. Developments in screening, prevention, biomarker, personalized therapies and chemotherapy have improved detection and treatment. However, despite these advances, many patients w...

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Detalhes bibliográficos
Publicado no:Onco Targets Ther
Main Authors: Al-Obeed, Omar, Vaali-Mohammed, Mansoor-Ali, Eldehna, Wagdy M, Al-Khayal, Khayal, Mahmood, Amer, Abdel-Aziz, Hatem A, Zubaidi, Ahmed, Alafeefy, Ahmed, Abdulla, Maha, Ahmad, Rehan
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2018
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5993033/
https://ncbi.nlm.nih.gov/pubmed/29892198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S148108
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