Synthesis and evaluation of anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities of some 3H-quinazolin-4-one derivatives

Some new 3H-quinazolin-4-one derivatives were synthesised and screened for anticancer, antiphospholipases, antiproteases, and antimetabolic syndrome activities. Compound 15d was more potent in reducing the cell viabilities of HT-29 and SW620 cells lines to 38%, 36.7%, compared to 5-FU which demonstr...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: El-Sayed, Nahed N. E., Almaneai, Norah M., Ben Bacha, Abir, Al-Obeed, Omar, Ahmad, Rehan, Abdulla, Maha, Alafeefy, Ahmed M.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6407576/
https://ncbi.nlm.nih.gov/pubmed/30821525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1574780
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