β-Phenethyl Isothiocyanate Induces Cell Death in Human Osteosarcoma through Altering Iron Metabolism, Disturbing the Redox Balance, and Activating the MAPK Signaling Pathway

Osteosarcoma is the most common primary malignancy of the skeleton in children and adults. The outcomes of people with osteosarcomas are unsatisfied. β-Phenethyl isothiocyanate (PEITC) exhibits chemoprevention and chemotherapeutic activities against many human cancers. The molecular mechanism underl...

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Bibliographic Details
Published in:Oxid Med Cell Longev
Main Authors: Lv, Huanhuan, Zhen, Chenxiao, Liu, Junyu, Shang, Peng
Format: Artigo
Language:Inglês
Published: Hindawi 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160723/
https://ncbi.nlm.nih.gov/pubmed/32322335
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2020/5021983
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