Epigenomic and Transcriptomic Changes During Human RPE EMT in a Stem Cell Model of Epiretinal Membrane Pathogenesis and Prevention by Nicotinamide

Epithelial to mesenchymal transition (EMT) is a biological process involved in tissue morphogenesis and disease that causes dramatic changes in cell morphology, migration, proliferation, and gene expression. The retinal pigment epithelium (RPE), which supports the neural retina, can undergo EMT, pro...

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Опубликовано в: :Stem Cell Reports
Главные авторы: Boles, Nathan C., Fernandes, Marie, Swigut, Tomasz, Srinivasan, Rajini, Schiff, Lauren, Rada-Iglesias, Alvaro, Wang, Qingjie, Saini, Janmeet S., Kiehl, Thomas, Stern, Jeffrey H., Wysocka, Joanna, Blenkinsop, Timothy A., Temple, Sally
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2020
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160390/
https://ncbi.nlm.nih.gov/pubmed/32243845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2020.03.009
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